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According to the Ozempic (semaglutide) patient medication information pamphlet, stomach pain is a common side effect that impacts 1 in 10 patients who use Ozempic. While stomach pain is common in Ozempic (semaglutide) patients, pancreatitis is also a potential side effect of the prescription.
According to the Novo Nordisk (makers of Ozempic) patient tear sheet, “Severe and on-going stomach pain which could be due to acute pancreatitis. If you have severe and on-going pain in the stomach area – see a doctor straight away as this could be a sign of acute pancreatitis (inflamed pancreas).”
Key Takeaways
Stomach pain can be seen in 1 in 10 patients who take Ozempic (semaglutide).
Acute pancreatitis is also a common side effect of Ozempic, especially if you’ve been diagnosed with pancreatitis in the past. Patients who experience ongoing stomach pain should see a primary care provider as soon as possible.
Regulating your meals into smaller portions, eating foods with less fat content, and starting with lower doses of Ozempic and increasing according to a prescribed schedule can help with stomach pain side effects.
Common Side Effects of Ozempic
Here are some of the common side effects of Ozempic according to Novo Nordisk:
Common (May Affect Up to 1 in 10 People)
“Feeling sick” or vomiting
Low blood sugar (hypoglycemia) when Ozempic® is used with an oral antidiabetic other than a sulfonylurea
Indigestion
Inflamed stomach (gastritis) - symptoms include stomach ache, nausea, or vomiting
Reflux or heartburn (gastro-esophageal reflux disease, GERD)
Stomach pain
Bloating of the stomach
Constipation
Burping
Gallstones
Feeling dizzy
Feeling tired
Weight loss
Less appetite
Gas (flatulence)
Increase of pancreatic enzymes (such as lipase and amylase)
Complications of diabetic eye disease (retinopathy)
Uncommon (May Affect Up to 1 in 100 People)
Change in the way food or drink tastes
Fast pulse
Injection site reactions (bruising, pain, irritation, itching, rash)
Allergic reactions (rash, itching, hives)
Delay in emptying of the stomach
Stomach Pain and Ozempic
Having stomach pain while taking Ozempic (semaglutide) is fairly common and does impact 1 in 10 patients. In addition to the stomach pain it can also cause cramping, bloating, aching, and gas pain (a dull and sharp occasional pain).
If you’re experiencing intermittent stomach pain, it shouldn’t be any cause for major concern. However, if you’ve had pancreatitis in the past or experience ongoing stomach pain, it’s advised to visit your primary care physician and ensure there’s no other serious issue occurring.
Ongoing Stomach Pain, Ozempic, and Pancreatitis
If you’re concerned that Ozempic might be a serious sign of pancreatitis, here are some ways to know whether this might be more of an acute problem.
Pancreatitis can cause a feeling of “severe” pain in the upper abdomen that can feel like its spreading to the chest.
Other symptoms include:
Pain that worsens after eating or drinking, or when lying flat on your back
Swelling and tenderness in the upper abdomen
Lowered blood pressure
Sweating
Clay-colored or greasy, foul-smelling stools
Bloating and fullness
Hiccups
Indigestion
A mild and yellowing of the skin and whites of the eyes (jaundice)
Weight loss
Shortness of breath
How to Avoid Stomach Pain When Taking Ozempic
Here are some tips to avoid stomach pain when taking Ozempic:
Smaller meals: Take smaller portions of meals more periodically throughout the day.
Increase your dosage over time: Try smaller doses of Ozempic (semaglutide) to ramp up your prescription total.
Avoid acidic foods: Avoid fruit juice and other acidic foods that might disrupt your natural stomach acid.
Try warm baths: Warm baths can sometimes reduce overall stomach pain feelings and help to reduce the concern that it may be related to pancreatitis.
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Sources
Novo Nordisk Canada Inc. (n.d.). Ozempic® Consumer Information. Retrieved from https://www.novonordisk.ca/content/dam/nncorp/ca/en/products/ozempic-consumer-information.pdf
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