Xifaxan (rifaximin) | Uses, Side Effects, Buy Online (Rifaximin)

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Brand Name

Xifaxanta 200mg Tablet

Prescription required. Can not be split. Product of UK/EU. Shipped from United Kingdom of Great Britain and Northern Ireland. Xifaxan is also marketed internationally under the name Xifaxanta.

$80.99 9 tablets
($9.00/ea)
$431.99 63 tablets
($6.86/ea)
$862.99 126 tablets
($6.85/ea)
$1,231.99 180 tablets
($6.84/ea)

Generic equivalent for Xifaxan

Rifaximin 200mg Tablet

Prescription required. May be split. Product of India. Shipped from Mauritius.

$136.99 100 tablets
($1.37/ea)
$227.99 200 tablets
($1.14/ea)

What are generics?

Brand Name

Sorry, we currently do not carry a brand option for this item.

Generic equivalent for Xifaxan

Rifaximin 400mg Tablet

Prescription required. May be split. Product of India. Shipped from Mauritius.

$156.99 100 tablets
($1.57/ea)
$281.99 200 tablets
($1.41/ea)

What are generics?

Brand Name

Xifaxan 550mg Tablet

Prescription required. Can not be split. Product of Australia. Shipped from Australia.

$917.99 56 tablets
($16.39/ea)
$1,761.99 112 tablets
($15.73/ea)
$2,624.99 168 tablets
($15.62/ea)

Generic equivalent for Xifaxan

Rifaximin 550mg Tablet

Prescription required. May be split. Product of India. Shipped from Mauritius.

$170.99 100 tablets
($1.71/ea)
$304.99 200 tablets
($1.52/ea)

What are generics?

What is Xifaxan (rifaximin)?

Xifaxan (rifaximin) is a rifamycin antibiotic that's used to treat people 12 years and older with travelers' diarrhea caused by the diagnosis of Escherichia coli (E. coli). Xifaxan (rifaximin) can also be used to treat irritable bowel syndrome with diarrhea (IBS-D) and prevent hepatic encephalopathy (HE) in adults. An elevated risk of hepatic encephalopathy is often associated with advanced liver disease or declining liver function.

To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more

Xifaxan (rifaximin) Dosage Information

Dosage information and scheduling should be provided by the prescribing healthcare provider. While your individual recommendation may vary, many dosing schedules are similar to those recommended by the manufacturer:

  • For IBS-D: 550 mg taken three times a day for 14 days. If symptoms return, this regimen may be used again. 

  • For Traveler’s Diarrhea: 200 mg taken three times a day for 3 days.

  • For Hepatic Encephalopathy: 550 mg taken twice a day. Daily use is recommended long-term for the prevention of symptoms. 

Condition

Dosage

Duration

Irritable Bowel Syndrome

550 mg, 3 times/day

14 days

Traveler’s Diarrhea

200 mg, 3 times/day

3 days

Hepatic Encephalopathy

550 mg, twice/day

Long-term use

Common Side Effects of Xifaxan (rifaximin)

The most common side effects of Xifaxan (rifaximin) are nausea and headache. 

Because Xifaxan is used at different doses and for different amounts of time depending on the diagnosis, the reported side effects during clinical trials have varied depending on the condition being treated. 

Common Side Effects:

  • Nausea

  • Headache

In clinical studies, patients using the recommended dose and duration of Xifaxan experienced some of the following side effects: 

Travelers' diarrhea:

  • Headache

Irritable Bowel Syndrome (IBS-D):

  • Nausea

  • Elevated liver enzymes

Hepatic Encephalopathy (HE):

  • Swelling in hands and feet

  • Nausea

  • Constipation

  • Dizziness

  • Tiredness

  • Urinary tract infection

  • Elevated liver enzymes

  • Extra abdominal fluid and swelling (ascites)

In rare cases, Xifaxan has been associated with a progressive rash or swelling of the face, tongue, or other areas that may impact breathing. If any of these symptoms arise after starting Xifaxan, seek prompt medical attention. 

Xifaxan is an antibiotic that removes harmful E. coli bacteria from the digestive tract. Many antibiotics, including Xifaxan, are associated with an elevated risk of an opportunistic Clostridium difficile (C. dif) infection. This can lead to inflammation in the colon and severe diarrhea. 

If you experience severe diarrhea, it’s critical to seek medical attention.

Rifaximin Information

Rifaximin (ri fax' I men) Xifaxan®

Rifaximin 200-mg tablets are used to treat traveler's diarrhea caused by certain bacteria in adults and children at least 12 years of age. Rifaximin 550-mg tablets are used to prevent episodes of hepatic encephalopathy (changes in thinking, behavior, and personality caused by a build-up of toxins in the brain in people who have liver disease) in adults who have liver disease and to treat irritable bowel syndrome (with diarrhea) in adults. Rifaximin is in a class of medications called antibiotics. Rifaximin treats traveler's diarrhea and irritable bowel syndrome by stopping the growth of the bacteria that cause diarrhea. Rifaximin treats hepatic encephalopathy by stopping the growth of bacteria that produce toxins and that may worsen liver disease. Rifaximin will not work to treat traveler's diarrhea that is bloody or occurs with fever. Antibiotics such as rifaximin will not work for colds, flu, or other viral infections. Taking antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

Rifaximin comes as a tablet to take by mouth with or without food. When rifaximin is used to treat traveler's diarrhea, it is usually taken three times a day for 3 days. When rifaximin is used to prevent episodes of hepatic encephalopathy, it is usually taken twice a day. When rifaximin is used to treat irritable bowel syndrome, it is usually taken three times a day for 14 days. To help you remember to take rifaximin, take it around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take rifaximin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. If you are taking rifaximin to treat traveler's diarrhea, your symptoms should improve within 24 to 48 hours after you start taking the medication. If your symptoms do not go away or they get worse, or if you develop a fever or bloody diarrhea, call your doctor. If you are taking rifamaxin to treat irritable bowel syndrome and your symptoms return after you have finished your treatment, call your doctor. Take rifaximin as directed, even if you feel better. If you are taking rifaximin to treat traveler's diarrhea or irritable bowel syndrome and you stop taking it too soon or if you skip doses, your infection may not be completely cured and the bacteria may become resistant to antibiotics. If you are taking rifaximin to prevent hepatic encephalopathy, do not stop taking it without talking to your doctor as you may experience symptoms of encephalopathy.

Before taking rifaximin, tell your doctor and pharmacist if you are allergic to rifaximin, rifabutin (Mycobutin), rifampin (Rifadin, Rifamate, Rifater, Rimactane), rifapentine (Priftin), any other medications, or any of the ingredients in rifaximin capsules. Ask your doctor or pharmacist for a list of the ingredients. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or have recently taken. Be sure to mention cyclosporine (Gengraf, Neoral, Restasis, Sandimmune) or other antibiotics. Your doctor may have to change the doses of your medications, monitor you carefully for side effects or treat your diarrhea differently. tell your doctor if you have or have ever had liver disease. tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking rifaximin, call your doctor.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Rifaximin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: nausea stomach pain dizziness excessive tiredness headache muscle tightening joint pain Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately: watery or bloody diarrhea that may occur along with stomach cramps and fever during your treatment or for 2 months afterward hives rash itching difficulty breathing or swallowing swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs hoarseness Rifaximin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Keep all appointments with your doctor. Do not let anyone else take your medication. Ask your pharmacist if you have any questions about refilling your prescription. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.

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