Prescription required. Can not be split. Product of UK/EU. Shipped from United Kingdom of Great Britain and Northern Ireland. Stendra is also marketed internationally under the name Spedra.
Prescription required. Can not be split. Product of UK/EU. Shipped from United Kingdom of Great Britain and Northern Ireland. Stendra is also marketed internationally under the name Spedra.
Prescription required. Can not be split. Product of UK/EU. Shipped from United Kingdom of Great Britain and Northern Ireland. Stendra is also marketed internationally under the name Spedra.
Stendra (avanafil) is used to help treat males with signs of sexual function problems (impotence or erectile dysfunction-ED). In combination with sexual stimulation, Stendra (avanafil) works by increasing the blood flow to the penis to assist a male in getting and maintaining an erection.
To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more
Here are general precautions when taking Stendra (Avanafil):
Precaution Area | Description |
Cardiovascular Risks | Should avoid use in patients with cardiovascular disease where sexual activity is inadvisable. This drug is not recommended for patients with recent MI, stroke, life-threatening arrhythmia, or severe high or low blood pressure. Monitor for any signs of vasodilatory effects (e.g., low blood pressure or dizziness). |
CYP3A4 Inhibitors | Do not use strong CYP3A4 inhibitors. Limit dose to 50 mg with moderate CYP3A4 inhibitors. Your healthcare providers can help you determine which prescription and over-the-counter products are safe to use with Stendra. |
Prolonged Erection | Seek immediate medical assistance for erections longer than 4 hours to avoid permanent damage. Use caution in patients with predispositions to priapism. |
Eye Effects | Discontinue if sudden vision loss occurs. |
Hearing Loss | Discontinue if sudden hearing loss occurs. |
Alpha-Blockers/Antihypertensives | May increase blood pressure-lowering effects in the body. Start at the lowest dose if used together. |
Alcohol | Substantial alcohol use (e.g., three or more drinks) can increase the risk of dangerous drops in blood pressure. Symptoms include dizziness upon standing, increased heart rate, and headache. |
Other ED Therapies | Not recommended for use with other PDE5 inhibitors or ED treatments. |
Bleeding Disorders | Safety is unknown in patients with bleeding disorders or active peptic ulceration. |
STDs | Does not protect against sexually transmitted diseases. |
Here are general dosage requirements for Stendra (Avanafil):
Use Case | Dose | Administration | Notes |
Erectile Dysfunction | Starting dose: 100 mg | Take orally as needed, 15 minutes before sexual activity | Dose can be increased to 200 mg or decreased to 50 mg based on efficacy and tolerability. Maximum once per day. |
Erectile Dysfunction with Food | 50 mg, 100 mg, or 200 mg | Can be taken with or without food | N/A |
Concomitant Alpha-Blockers | 50 mg | Patients should be stable on alpha-blocker therapy before starting STENDRA | Initiate at 50 mg dose |
Concomitant Moderate CYP3A4 Inhibitors | 50 mg | Not to exceed once every 24 hours | Includes erythromycin, diltiazem, fluconazole, etc. |
Concomitant Strong CYP3A4 Inhibitors | Do not use | N/A | Includes ketoconazole, ritonavir, etc. |
Concomitant Nitrates | Contraindicated | N/A | Increases the blood pressure-lowering effects of nitrates |
Guanylate Cyclase Stimulators | Contraindicated | N/A | Increases the blood pressure-lowering effects |
If you experience side effects, discussing your concerns with your healthcare provider is important. Here are some of the common and less common side effects of Stendra (avanafil).
Common side effects include:
Headache
Flushing
Nasal congestion
Cold or flu-like symptoms
Back pain
More rare side effects include:
Blurred vision
Dizziness
Rapid heart rate
Chest pain
Excessive sweating
Frequent urge to urinate
Difficult or labored breathing
Erection lasting longer than 4 hours
Other common questions:
It’s recommended that your first 100 mg be taken as a single and no more than once a day. Usually taken 15 minutes before sexual intercourse. Your primary care physician may decide to adjust your dose if needed. The maximum dose is 200 mg per day, but it’s important not to change your dose without first speaking with your healthcare provider.
It’s recommended that you do not drink excessive amounts of alcohol when taking Stendra (avanafil). Drinking three or more alcoholic beverages can increase your chances of dangerous drops in blood pressure. Initial symptoms include headache, dizziness, and increased heart rate.
Avanafil (a van' a fil) Stendra®
Avanafil is used to treat erectile dysfunction (ED: impotence; inability to get or keep an erection in men). Avanafil is in a class of medications called phosphodiesterase (PDE) inhibitors. It works by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Avanafil does not cure erectile dysfunction or increase sexual desire. Avanafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV).
Avanafil comes as a tablet to take by mouth. For men taking the 100- mg or 200-mg doses, avanafil is usually taken with or without food as needed, about 15 minutes before sexual activity. For men taking the 50-mg dose, avanafil is usually taken with or without food as needed, about 30 minutes before sexual activity. Do not take avanafil more often than once in 24 hours. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take avanafil exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Your doctor will probably start you on an average dose of avanafil and may increase or decrease your dose depending on how you respond to the medication. Tell your doctor if avanafil is not working well or if you experience side effects. Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
Before taking avanafil, tell your doctor and pharmacist if you are allergic to avanafil, any other medications, or any of the ingredients in avanafil tablets. Ask your pharmacist or check the patient information for a list of the ingredients. do not take avanafil if you are taking or have recently taken riociguat (Adempas) or nitrates such as isosorbide dinitrate (Dilatrate-SR, Isordil, in BiDil), isosorbide mononitrate (Monoket), and nitroglycerin (Minitran, Nitro-Dur, Nitromist, Nitrostat, others). Nitrates come as tablets, sublingual (under the tongue) tablets, sprays, patches, pastes, and ointments. Ask your doctor if you are not sure if any of your medications contain nitrates. do not take street drugs containing nitrates such as amyl nitrate and butyl nitrate ('poppers') while taking avanafil. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: alpha blockers such as alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), tamsulosin (Flomax, in Jalyn), silodosin (Rapaflo), and terazosin; certain antifungal medications such as fluconazole (Diflucan), itraconazole (Onmel, Sporanox), and ketoconazole (Nizoral); aprepitant (Emend); clarithromycin (Biaxin, in Prevpac); diltiazem (Cardizem, Cartia, Tiazac); erythromycin (E.E.S, E-Mycin, Erythrocin); HIV protease inhibitors such as atazanavir (Reyataz, in Evotaz), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra), and saquinavir (Invirase); other medications or treatments for erectile dysfunction; medications for high blood pressure; nefazodone; verapamil (Calan, Covera, Verelan, others); and telithromycin (Ketek). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with avanafil, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. tell your doctor if you have ever been advised by a doctor to avoid sexual activity for medical reasons, if you have had heart surgery within the past 6 months and if you have ever had an erection that lasted longer than 4 hours. Also tell your doctor if you have or have ever had a condition that affects the shape of the penis such as angulation, cavernosal fibrosis, or Peyronie's disease; a heart attack; a stroke; an irregular heartbeat; a blocked artery; angina (chest pain); high or low blood pressure; heart failure; blood cell problems such as sickle cell anemia (a disease of the red blood cells), multiple myeloma (cancer of the plasma cells), or leukemia (cancer of the white blood cells); ulcers; bleeding problems; or liver or kidney disease. Also tell your doctor if you have or have ever had retinitis pigmentosa (a rare inherited eye disease) or if you have ever had severe vision loss, especially if you were told that the vision loss was caused by a blockage of blood flow to the nerves that help you see. you should know that avanafil is only for use in males. Women should not take avanafil, especially if they are or may become pregnant or are breastfeeding. If a pregnant woman takes avanafil, she should call her doctor. talk to your doctor about the safe use of alcoholic beverages during your treatment with avanafil. If you drink a large amount of alcohol (more than three glasses of wine or three shots of whiskey) while you are taking avanafil you are more likely to experience certain side effects of avanafil such as dizziness, headache, fast heartbeat, and low blood pressure. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking avanafil. you should know that sexual activity may be a strain on your heart, especially if you have heart disease. If you have chest pain, dizziness, or nausea during sexual activity, call your doctor immediately and avoid sexual activity until your doctor tells you otherwise. tell all your healthcare providers that you are taking avanafil. If you ever need emergency medical treatment for a heart problem, the healthcare providers who treat you will need to know when you last took avanafil.
Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medication.
Avanafil may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: headache flushing back pain Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment: an erection that lasts longer than 4 hours sudden loss of vision in one or both eyes (see below for more information) sudden hearing loss (see below for more information) ringing in the ears dizziness rash itching swollen eyelids Avanafil may cause other side effects. Call your doctor if you have any unusual problems while taking this medication. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). Some patients experienced a sudden loss of some or all of their vision after they took medications that are similar to avanafil. The vision loss was permanent in some cases. It is not known if the vision loss was caused by the medication. If you experience a sudden loss of vision while you are taking avanafil, call your doctor immediately. Do not take any more doses of avanafil or similar medications such as sildenafil (Revatio, Viagra), tadalafil (Cialis) or vardenafil (Levitra) until you talk to your doctor. Some patients experienced a sudden decrease or loss of hearing after they took other medications that are similar to avanafil. The hearing loss usually involved only one ear and did not always improve when the medication was stopped. It is not known if the hearing loss was caused by the medication. If you experience a sudden loss of hearing, sometimes with ringing in the ears or dizziness, while you are taking avanafil, call your doctor immediately. Do not take any more doses of avanafil or similar medications such as sildenafil (Revatio, Viagra), tadalafil (Cialis) or vardenafil (Levitra) until you talk to your doctor.
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
Keep all appointments with your doctor. Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.