Prescription required. Can not be split. Product of Canada. Shipped from Canada.
Dyazide (triamterene/hydrochlorothiazide) is generally used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This medication is a combination of two "water pills" (diuretics): triamterene and hydrochlorothiazide.
The combination of these two water pills is used by people who have developed or are currently at risk for having low potassium levels on hydrochlorothiazide alone. This medication can cause you to make more urine, which helps your body get rid of extra salt and water. Dyazide (triamterene/hydrochlorothiazide) can also reduce swelling caused by extra fluid in the body (edema) related to conditions like heart failure, liver disease, or kidney disease.
To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more
Here are general precautions when taking Dyazide (Triamterene / Hydrochlorothiazide):
Category | Precaution |
General Precautions | Triamterene tends to conserve potassium and can cause hyperkalemia in the body, sometimes leading to cardiac irregularities. Use may aggravate electrolyte imbalances, so following up on routine labwork is important. It’s important to monitor kidney function before and after starting Dyazide. Individuals with a history of liver disease should use caution before starting Dyazide. Dyazide should be used with caution in patients with a history of kidney stones. |
Laboratory Tests | Normal adult blood potassium levels are 3.5 to 5.0 mEq/L. Dyazide's triamterene component can raise potassium levels, causing symptoms like nausea, diarrhea, muscle weakness, or chest pain. Elevated potassium levels are dangerous and require prompt medical attention. It’s important to continue to monitor lab values over time. |
Drug Interactions | Lithium: monitor serum levels due to increased risk of toxicity. NSAIDs: use caution due to the potential for acute renal failure. Additive effects can be seen with other blood pressure medications like ACE inhibitors, diuretics, anesthetics, and muscle relaxants. It’s important to avoid other medications that also increase potassium unless use is explicitly advised by a healthcare provider who is aware of all your medications. |
Drug & Laboratory Test Interactions | Interferes with fluorescent measurement of quinidine. |
Carcinogenesis & Mutagenesis | Increased incidence of hepatocellular neoplasia in mice at high doses. No mutagenic effects in bacterial studies. |
Pregnancy | No teratogenic effects were observed in animal studies, but safe use during pregnancy has not been firmly established. Use during pregnancy only if clearly needed, under the guidance of a healthcare professional. Crosses placental barrier. |
Nursing Mothers | Likely present in human milk. Use only if essential; patients are advised to stop nursing if Dyazide therapy is continued. |
Pediatric Use | Safety and effectiveness not established in pediatric patients. |
Here are general dosage requirements for Dyazide (Triamterene / Hydrochlorothiazide):
Scenario | Dosage Guidelines |
Usual Starting Dose (Alone) | Once daily, often recommended in the morning |
Combined with Diuretic/Antihypertensive | Initial lower dosage of each agent, then adjusted to patient's needs |
Maximum Daily Dosage | 37.5 mg / 25 mg |
Switching from Other Diuretics | Discontinue all potassium supplementation when switching to triamterene capsules |
Adding to Other Diuretic Therapy | Discontinue all potassium supplementation when adding triamterene capsules to existing diuretic therapy |
Common side effects include the following:
Dizziness
Elevated potassium levels
Nausea
Diarrhea
Fatigue
Muscle cramps
If you experience these side effects or feel that they are not resolving or becoming worse after several days, it’s important to talk with your healthcare provider.
In rare cases, the components of Dyazide have been associated with serious side effects. If you experience a skin rash, contact your healthcare provider immediately. In some cases, this may be a sign of an allergic reaction or a more serious skin condition known as Stevens-Johnson syndrome (SJS). Dyazide has also been associated with changes in vision, like blurry vision or tunnel vision.
Other common questions:
Triamterene is a drug used for the management and treatment of high blood pressure and edema (swelling due to excess fluid). It is in the potassium-sparing diuretics class of drugs.
Triamterene and Hydrochlorothiazide (trye am' ter een) (hye'' droe klor'' oh thye' a zide) Dyazide® (as a combination product containing Triamterene, Hydrochlorothiazide) Maxzide® (as a combination product containing Triamterene, Hydrochlorothiazide)
The combination of triamterene and hydrochlorothiazide is used to treat high blood pressure and edema (fluid retention; excess fluid held in body tissues) in patients who have lower amounts of potassium in their bodies or for whom low potassium levels in the body could be dangerous. The combination of triamterene and hydrochlorothiazide is in a class of medications called diuretics ('water pills'). They work by causing the kidneys to get rid of unneeded water and salt from the body into the urine.
High blood pressure is a common condition, and when not treated it can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.
The combination of triamterene and hydrochlorothiazide comes as a capsule and tablet to take by mouth. It usually is taken once a day. Take triamterene and hydrochlorothiazide at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take triamterene and hydrochlorothiazide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. This medication controls high blood pressure and edema but does not cure these conditions. Continue to take triamterene and hydrochlorothiazide even if you feel well. Do not stop taking triamterene and hydrochlorothiazide without talking to your doctor.
Before taking triamterene and hydrochlorothiazide,
tell your doctor and pharmacist if you are allergic to triamterene, hydrochlorothiazide, sulfonamide-derived medications ('sulfa drugs'), any other medications, or any ingredients in triamterene and hydrochlorothiazide capsules or tablets. Ask your pharmacist or check the patient information for a list of the ingredients.
do not take triamterene and hydrochlorothiazide if you are taking amiloride (Midamor), spironolactone (Aldactone, in Aldactazide), or other medications containing triamterene. Your doctor will probably tell you not to take triamterene and hydrochlorothiazide if you are taking one of these medications.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: amphotericin B (Abelcet, Ambisome, Amphotec); angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin, in Lotrel), captopril (Capoten), enalapril (Vasotec, Vaseretic), fosinopril, lisinopril (in Prinzide, in Zestoretic), moexipril (Univasc, in Uniretic), perindopril (Aceon), quinapril (Accupril, in Accuretic), ramipril (Altace), and trandolapril (Mavik, in Tarka); anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); barbiturates such as phenobarbital; corticosteroids such as betamethasone (Celestone), budesonide (Entocort), cortisone (Cortone), dexamethasone (Decadron, Dexpak, Dexasone, others), fludrocortisone (Floriner), hydrocortisone (Cortef, Hydrocortone), methylprednisolone (Medrol, Meprolone, others), prednisolone (Prelone, others), prednisone (Rayos), and triamcinolone (Aristocort, Azmacort); corticotropin (ACTH, H.P., Acthar Gel); digoxin (Lanoxin); laxatives; lithium (Lithobid); medications for diabetes, gout, or high blood pressure; methenamine (Hiprex, Urex); narcotic pain relievers; nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); oral steroids such as dexamethasone , methylprednisolone (Medrol), and prednisone (Rayos); and potassium supplements or potassium-containing medication supplements. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
tell your doctor if you have kidney disease or high blood levels of potassium. Your doctor may tell you not to take triamterene and hydrochlorothiazide.
tell your doctor if you have or have ever had kidney stones, systemic lupus erythematosus (SLE, a chronic inflammatory condition), diabetes, gout, or thyroid, heart, or liver disease.
tell your doctor if you are pregnant or plan to become pregnant. Do not breastfeed if you are taking triamterene and hydrochlorothiazide. If you become pregnant while taking triamterene and hydrochlorothiazide, call your doctor.
if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking triamterene and hydrochlorothiazide.
plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Triamterene and hydrochlorothiazide may make your skin sensitive to sunlight.
you should know that triamterene and hydrochlorothiazide may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common when you first start taking triamterene and hydrochlorothiazide. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up. Alcohol can add to these side effects.
If your doctor prescribes a low-salt or low-sodium diet, or to eat or drink increased amounts of potassium-rich foods (e.g., bananas, prunes, raisins, and orange juice) in your diet, follow these instructions carefully.
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Triamterene and hydrochlorothiazide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: frequent urination headache Some side effects can be serious. If you experience any of these symptoms or those listed in the SPECIAL PRECAUTIONS section, call your doctor immediately or seek emergency medical treatment: dry mouth; thirst; nausea; vomiting; weakness, tiredness; drowsiness; restlessness; confusion; muscle weakness, pain, or cramps; fast heartbeat and other signs of dehydration and electrolyte imbalance rash hives itching difficulty breathing or swallowing pain in the upper stomach area swelling or tenderness of stomach area upset stomach fever unusual bruising or bleeding loss of appetite yellowing of skin or eyes flu-like symptoms feelings of numbness, tingling, pricking, burning, or creeping on the skin inability to move arms and legs slow or irregular heartbeat If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
Keep this medicine in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to triamterene. Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking triamterene and hydrochlorothiazide. Do not let anyone else take your medicine. Ask your pharmacist any questions you have about refilling your prescription. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.
