7 Places to Buy Levothyroxine Online (Guide)

Matthew Sommers Medically reviewed by Matthew Sommers on

6 min read

Thyroid Protection Treatment with Synthroid (Levothyroxine)

Synthroid (levothyroxine sodium) is a prescription thyroid medication that replaces the hormone normally produced by the thyroid gland, essential for regulating energy and metabolism. It is primarily used to treat hypothyroidism when the body does not produce enough thyroid hormone. Synthroid is also used alongside surgery and radioiodine therapy to manage well-differentiated thyroid cancer. While widely prescribed, it should not be used for weight loss, as misuse—especially with larger doses being used as weight-loss drugs—can lead to severe or fatal side effects.

Before taking Synthroid (levothyroxine sodium), inform your doctor if you have a history of adrenal gland disorders, thyrotoxicosis, heart conditions, or recent radiation therapy. Certain conditions, such as osteoporosis, anemia, diabetes, or thyroid nodules, may also require monitoring or dosage adjustments. 

If you become pregnant, do not stop taking Synthroid (levothyroxine sodium) without consulting your doctor, as thyroid hormone levels are crucial during pregnancy. Proper medical guidance ensures safe and effective use of this medication.

Key Takeaways

  • Medical Use and Effectiveness: Synthroid (levothyroxine) is a prescription thyroid medication used to treat hypothyroidism by replacing thyroid hormone, essential for metabolism and energy regulation. It is also used in thyroid cancer management but should not be misused for weight loss due to serious risks.

  • Availability and Pricing: Synthroid and its generic equivalents can be purchased online, with prices varying by provider. Generic levothyroxine is available for as low as $11 at Sesame Care, while branded Synthroid costs around $47.67 at DrugMart. Amazon Pharmacy and international providers like PlanetDrugsDirect offer competitive pricing and reliable delivery.

  • Safety and Side Effects: Common side effects include headache, insomnia, increased heart rate, and nervousness, while serious reactions such as chest pain and irregular heartbeat require immediate medical attention. Patients should take levothyroxine on an empty stomach and avoid interactions with calcium, iron, and antacids. Regular monitoring ensures proper dosage adjustments.

7 Places to Buy Synthroid (Levothyroxine Sodium) Online

Synthroid (levothyroxine sodium) can be conveniently purchased from several online pharmacies:

Provider

Prescription Required

Same-Day Pickup Available

Price

PlanetDrugsDirect

Yes

No

Available in 25mcg to 300mcg tablets - pricing ranging anywhere from $38.99 for 30 tablets to $50.99 for 90 tablets depending on mcg

DrugMart.com

Yes

No

Branded Synthroid - 90 tablets for $47.67 (25 mcg tablets)

Amazon Pharmacy

Yes

No

$51.90

Sesame Care

Yes

No

As low as $11 for generic equivalents

Honeybee Health

Yes

No

$15.00 for generic equivalents

Health Warehouse

Yes

No

$129.00

RXConnected

Yes

No

$35.00

Prices updated March 2025.

1. PlanetDrugsDirect – Top Pick

Price: $38.99 for 30 tablets to $50.99 for 90 tablets (dosages from 25mcg to 300mcg)

Why Choose PlanetDrugsDirect?

  • Affordable generic Levothyroxine pricing.

  • Multiple dosage options available for different prescription needs.

  • Reliable international pharmacy service with safe prescription fulfillment.

Cons:

  • No same-day pickup.

  • Shipping times may be longer than U.S.-based pharmacies.

2. DrugMart.com

Price: $47.67 for 90 tablets (25 mcg)

Why Choose DrugMart.com?

  • Offers branded Synthroid, which some patients prefer for consistency and effectiveness.

  • Fast shipping across the U.S.

  • User-friendly ordering system for easy prescription uploads.

Cons:

  • No same-day pickup available.

  • Fewer promotional discounts compared to other platforms.

Purchase directly from DrugMart.com

3. Amazon Pharmacy

Price: $51.90

Why Choose Amazon Pharmacy?

  • Secure online ordering with automated refills available.

  • Discounts for Amazon Prime members.

  • Fast home delivery through Amazon’s shipping network.

Cons:

  • Requires an Amazon account.

  • No in-store pickup.

Visit Amazon Pharmacy

4. Sesame Care

Price: As low as $11 for generic equivalents

Why Choose Sesame Care?

  • Telehealth services available—patients can consult a physician for a prescription.

  • No insurance required, making it cost-effective for uninsured patients.

  • Access to licensed healthcare providers for personalized guidance.

Cons:

  • Prices may vary depending on consultation fees and prescription approvals.

Visit Sesame Care

5. Honeybee Health

Price: $15.00 for generic Levothyroxine

Why Choose Honeybee Health?

  • No insurance required—prices are transparent with no hidden fees.

  • Affordable rates for generic Levothyroxine.

  • Discreet shipping available.

Cons:

  • Only offers generic versions of Levothyroxine.

  • No same-day pickup.

Visit Honeybee Health

6. Health Warehouse

Price: $129.00

Why Choose Health Warehouse?

  • Licensed and accredited U.S. online pharmacy.

  • Strict pharmacy regulations ensure quality and safety.

  • Home delivery available.

Cons:

  • Higher price compared to other providers.

  • Prescription verification may take longer.

Visit Health Warehouse

7. RXConnected

Price: $35.00

Why Choose RXConnected?

  • Offers discounted pricing for generic Levothyroxine.

  • Availability of both U.S. and international prescription drugs.

  • Secure and verified ordering process.

Cons:

  • Longer shipping times for international orders.

  • Some regulatory restrictions based on location.

Visit RXConnected

Available Dosages & Forms

Levothyroxine is available in tablet and liquid formulations, with dosages ranging from 25 mcg to 300 mcg. Your healthcare provider will determine the correct dose based on your thyroid function tests and medical history.

Proper Storage of Levothyroxine

  • Store at room temperature (68°F to 77°F / 20°C to 25°C).

  • Keep in a dry place, away from moisture and direct sunlight.

  • Do not store medication in the bathroom.

  • Keep in the original container to protect from light and contamination.

Common Side Effects

Levothyroxine is generally well-tolerated, but some individuals may experience mild side effects, including:

  • Headache

  • Insomnia

  • Increased heart rate

  • Sweating

  • Weight loss

  • Anxiety or nervousness

If these symptoms persist or worsen, contact your healthcare provider.

Serious Side Effects

Although rare, serious side effects may occur, such as:

  • Chest pain

  • Irregular heartbeat

  • Shortness of breath

  • Seizures

  • Extreme fatigue

Seek immediate medical attention if you experience any severe reactions.

Common Questions About Synthroid (Levothyroxine Sodium)

Common questions and answers about Synthroid (levothyroxine sodium):

1. What is Levothyroxine used for? 

Levothyroxine is prescribed to treat hypothyroidism by replacing or supplementing the thyroid hormone.

2. How should Levothyroxine be taken? 

Levothyroxine should be taken once daily on an empty stomach, at least 30 to 60 minutes before breakfast.

3. Can Levothyroxine be taken with other medications? 

Certain medications, including calcium supplements, iron supplements, and antacids, can interfere with Levothyroxine absorption. Consult your doctor before combining treatments.

4. What happens if I miss a dose? 

If you miss a dose, take it as soon as you remember. However, if it’s close to the next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.

5. What is the cheapest place to buy Levothyroxine? 

Prices vary across pharmacies, but online providers like DrugMart.com, Honeybee Health, and Health Warehouse often offer competitive pricing.

6. How long does it take for Levothyroxine to work? 

Improvement in symptoms may take several weeks. Regular blood tests are necessary to ensure proper dosage adjustments.

Rely on PlanetDrugsDirect.com to Buy Online Synthroid (Levothyroxine Sodium)

As a trusted prescription referral service, we offer important benefits whenever you order online. Each of our partner pharmacies and/or government-approved dispensaries is committed to providing the best experience possible of any online prescription referral service on the internet. We offer:

  • Low prices

  • Quick turn-around times

  • Generic and brand-name medications

  • Unparalleled customer service


Sources

  1. U.S. Food and Drug Administration. (2022). Levothyroxine sodium tablets, USP: Prescribing information (021402s036). Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/021402s036lbl.pdf


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The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.