
Zovirax Topical (acyclovir) is an antiviral medication used for the treatment of herpes simplex virus (HSV) infections affecting the skin. While it does not cure herpes, it can help reduce the severity and duration of outbreaks when used as directed.
Zovirax Topical Cream: Indicated for the treatment of recurrent herpes labialis (cold sores) on the lips and face in immunocompetent individuals.
Zovirax Topical Ointment: Used for the treatment of initial genital herpes lesions and mucocutaneous HSV infections in immunocompromised patients.
Acyclovir does not prevent future outbreaks or transmission of Herpes Simplex Virus (HSV). Patients should follow preventive measures to reduce the risk of spreading the virus.
Key Takeaways
Medical Use and Effectiveness: Zovirax (acyclovir) is an antiviral topical treatment for herpes simplex virus (HSV) infections. The cream is used for cold sores (herpes labialis) in immunocompetent individuals, while the ointment is prescribed for initial genital herpes and mucocutaneous HSV in immunocompromised patients. It does not cure herpes or prevent future outbreaks.
Availability and Pricing: Zovirax Cream is available online through various pharmacies, with prices ranging from $50.99 for a generic equivalent at PlanetDrugsDirect to $204.50 for branded Zovirax on Amazon.
Safety and Usage Considerations: Common side effects include skin dryness, irritation, and mild burning at the application site. Serious allergic reactions are rare but require medical attention. The medication should not be used in children under 12, and pregnant or breastfeeding patients should consult a physician. Preventive measures, such as handwashing and avoiding direct contact with infected areas, are recommended to reduce transmission risk.
4 Places to Buy Zovirax Cream (Acyclovir) Online
If you’re looking to buy Zovirax Cream (Acyclovir) online, here are the best places to purchase it along with their pricing details:
Pharmacy | Price |
$82.00 for brand name Zovirax, $50.99 for generic equivalent | |
Amazon | $204.50 for brand name Zovirax |
HealthWarehouse | $223 for generic equivalent |
Sesame Health | Prices Vary |
Prices updated March 2025.
1. PlanetDrugsDirect — Top Pick
Price: $82.00 for brand name Zovirax, $50.99 for generic equivalent
Why Choose PlanetDrugsDirect?
Trusted CIPA-certified international pharmacy with competitive pricing.
Reliable customer service and safe medication sourcing.
Ready to purchase? Buy from PlanetDrugsDirect.
2. Amazon Pharmacy
Price: $204.50 for brand name Zovirax
Why Choose Amazon Pharmacy?
Fast and reliable delivery options.
Convenient online ordering with customer reviews for reference.
3. HealthWarehouse
Price: $223 for generic equivalent
Why Choose HealthWarehouse?
Licensed U.S. pharmacy with FDA-approved medications.
Offers reliable shipping and competitive pricing.
4. Sesame Health
Price: Prices Vary
Why Choose Sesame Health?
Provides telehealth consultations and prescription services.
Offers potential discounts based on membership and insurance.
Dosage
Zovirax Cream dosage schedule is as follows:
Zovirax Cream (Herpes Labialis Treatment)
Apply 5 times daily at approximately 4-hour intervals, omitting the overnight dose.
Treatment should be initiated at the earliest sign of herpes labialis, such as during the prodromal phase (tingling, burning, or itching sensation) or when lesions first appear.
Duration of therapy: 4 days or as directed by a healthcare provider.
Use a clean fingertip or cotton swab for application to prevent contamination and viral spread.
Adolescent and Pediatric Use
For adolescents 12 years of age and older, the recommended dosage is the same as for adults.
Safety and efficacy have not been established in children under 12 years of age.
Storage
Store at controlled room temperature (20°C to 25°C / 68°F to 77°F).
Keep the medication in its original container with the cap tightly closed.
Do not freeze or refrigerate.
Keep out of reach of children and pets.
Side Effects
Here are the common and less common side effects of Zivoriax (Acyclovir):
Common Side Effects
Dry, cracked, or peeling lips.
Skin dryness or flaking at the application site.
Burning, stinging, or itching upon application.
Serious Reactions (Seek Medical Attention Immediately)
Signs of an allergic reaction such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.
If severe irritation, redness, or rash develops at the application site.
Warnings
Medical Consultation Required: Inform your physician of any existing conditions, allergies, or current medications.
Contraindications: Do not use if allergic to acyclovir or valacyclovir (Valtrex).
Not for Use in Children Under 12.
Pregnancy Considerations: The effects on an unborn child are unclear. However, herpes can be transmitted to the infant during childbirth. Patients with genital herpes should consult their physician for management during pregnancy.
Breastfeeding Precaution: Avoid breastfeeding if active herpes lesions are present on or near the breast.
Infection Prevention:
Avoid direct skin contact with others to prevent virus transmission.
Use latex condoms during sexual intercourse.
Wash hands frequently and avoid touching infected areas.
Drug Interactions
Minimal systemic absorption: Drug interactions are unlikely but should still be discussed with a physician.
Inform your doctor about all prescription, over-the-counter, vitamin, and herbal medications you are taking.
For additional details or adverse event reporting, contact the FDA at 1-800-FDA-1088.
Rely on PlanetDrugsDirect.com to Buy Online Zovirax Cream (Acyclovir)
As a trusted prescription referral service, we offer important benefits whenever you order online. Each of our partner pharmacies and/or government-approved dispensaries is committed to providing the best experience possible of any online prescription referral service on the internet. We offer:
Low prices
Quick turn-around times
Generic and brand-name medications
Unparalleled customer service
Sources
Zovirax (acyclovir) [package insert]. U.S. Food and Drug Administration. Updated 2005. Accessed March 7, 2025. https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/018828s030%2C020089s019%2C019909s020lbl.pdf